The dysregulated innate immune response in severe COVID-19 pneumonia that could drive poorer outcome

BACKGROUND: Although immune modulation is a promising therapeutic avenue in coronavirus disease 2019 (COVID-19), the most relevant targets remain to be found. COVID-19 has peculiar characteristics and outcomes, suggesting a unique immunopathogenesis. METHODS: Thirty-six immunocompetent non-COVID-19...

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Detalhes bibliográficos
Publicado no:J Transl Med
Main Authors: Blot, Mathieu, Bour, Jean-Baptiste, Quenot, Jean Pierre, Bourredjem, Abderrahmane, Nguyen, Maxime, Guy, Julien, Monier, Serge, Georges, Marjolaine, Large, Audrey, Dargent, Auguste, Guilhem, Alexandre, Mouries-Martin, Suzanne, Barben, Jeremy, Bouhemad, Belaid, Charles, Pierre-Emmanuel, Chavanet, Pascal, Binquet, Christine, Piroth, Lionel
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7711269/
https://ncbi.nlm.nih.gov/pubmed/33272291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-020-02646-9
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