Prognostic Biomarker TP53 Mutations for Immune Checkpoint Blockade Therapy and Its Association With Tumor Microenvironment of Lung Adenocarcinoma

Immune checkpoint inhibitors (ICIs), is characterized by durable responses and improved survival in non-small cell lung cancer (NSCLC). However, there is a lack of predictive biomarkers to optimize the use of ICIs in cancers. The clinical benefit of patients with lung adenocarcinoma (LUAD) harboring...

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Udgivet i:Front Mol Biosci
Main Authors: Lin, Xinqing, Wang, Liqiang, Xie, Xiaohong, Qin, Yinyin, Xie, Zhanhong, Ouyang, Ming, Zhou, Chengzhi
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Molecular Biosciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7710974/
https://ncbi.nlm.nih.gov/pubmed/33330629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2020.602328
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