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Prospects of Directly Reprogrammed Adult Human Neurons for Neurodegenerative Disease Modeling and Drug Discovery: iN vs. iPSCs Models

A reliable disease model is critical to the study of specific disease mechanisms as well as for the discovery and development of new drugs. Despite providing crucial insights into the mechanisms of neurodegenerative diseases, translation of this information to develop therapeutics in clinical trials...

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Bibliografiske detaljer
Udgivet i:Front Neurosci
Main Authors: Zhang, Ying, Xie, Xinyang, Hu, Jiangnan, Afreen, Kazi Sabrina, Zhang, Chun-Li, Zhuge, Qichuan, Yang, Jianjing
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7710799/
https://ncbi.nlm.nih.gov/pubmed/33328842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2020.546484
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