Radiation-induced DNA damage and repair effects on 3D genome organization

The three-dimensional structure of chromosomes plays an important role in gene expression regulation and also influences the repair of radiation-induced DNA damage. Genomic aberrations that disrupt chromosome spatial domains can lead to diseases including cancer, but how the 3D genome structure resp...

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Bibliografske podrobnosti
izdano v:Nat Commun
Main Authors: Sanders, Jacob T., Freeman, Trevor F., Xu, Yang, Golloshi, Rosela, Stallard, Mary A., Hill, Ashtyn M., San Martin, Rebeca, Balajee, Adayabalam S., McCord, Rachel Patton
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2020
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7710719/
https://ncbi.nlm.nih.gov/pubmed/33268790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-20047-w
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