Optogenetic Tuning Reveals Rho Amplification-Dependent Dynamics of a Cell Contraction Signal Network

Local cell contraction pulses play important roles in tissue and cell morphogenesis. Here, we improve a chemo-optogenetic approach and apply it to investigate the signal network that generates these pulses. We use these measurements to derive and parameterize a system of ordinary differential equati...

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Bibliografske podrobnosti
izdano v:Cell Rep
Main Authors: Kamps, Dominic, Koch, Johannes, Juma, Victor O., Campillo-Funollet, Eduard, Graessl, Melanie, Banerjee, Soumya, Mazel, Tomáš, Chen, Xi, Wu, Yao-Wen, Portet, Stephanie, Madzvamuse, Anotida, Nalbant, Perihan, Dehmelt, Leif
Format: Artigo
Jezik:Inglês
Izdano: Cell Press 2020
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7710677/
https://ncbi.nlm.nih.gov/pubmed/33264629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2020.108467
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