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Auto-antibodies to p53 and the subsequent development of colorectal cancer in a United States prospective cohort consortium

BACKGROUND: Auto-antibodies to tumor suppressor p53 are found in a subset of colorectal cancer (CRC) patients. A recent prospective study in the US has reported a significant 1.8-fold increased odds for CRC development with pre-diagnostic sero-positivity to p53. In the present study, we sought to ex...

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Detalhes bibliográficos
Publicado no:Cancer Epidemiol Biomarkers Prev
Main Authors: Butt, Julia, Blot, William J., Visvanathan, Kala, Le Marchand, Loïc, Wilkens, Lynne R., Chen, Yu, Sesso, Howard D., Teras, Lauren, Ryser, Marc D., Hyslop, Terry, Wassertheil-Smoller, Sylvia, Tinker, Lesley F., Potter, John D., Song, Mingyang, Berndt, Sonja I., Waterboer, Tim, Pawlita, Michael, Epplein, Meira
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7710535/
https://ncbi.nlm.nih.gov/pubmed/32972968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1055-9965.EPI-20-0780
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