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Morphine‐mediated release of miR‐138 in astrocyte‐derived extracellular vesicles promotes microglial activation

Opioids, such as morphine, are the mainstay for the management of postsurgical pain. Over the last decade there has been a dramatic increase in deaths related to opioid overdose. While opioid abuse has been shown to result in increased neuroinflammation, mechanism(s) underlying this process, remain...

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Detalhes bibliográficos
Publicado no:J Extracell Vesicles
Main Authors: Liao, Ke, Niu, Fang, Hu, Guoku, Yang, Lu, Dallon, Blake, Villarreal, Delaney, Buch, Shilpa
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7710131/
https://ncbi.nlm.nih.gov/pubmed/33304479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jev2.12027
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