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Morphine‐mediated release of miR‐138 in astrocyte‐derived extracellular vesicles promotes microglial activation

Opioids, such as morphine, are the mainstay for the management of postsurgical pain. Over the last decade there has been a dramatic increase in deaths related to opioid overdose. While opioid abuse has been shown to result in increased neuroinflammation, mechanism(s) underlying this process, remain...

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Podrobná bibliografie
Vydáno v:J Extracell Vesicles
Hlavní autoři: Liao, Ke, Niu, Fang, Hu, Guoku, Yang, Lu, Dallon, Blake, Villarreal, Delaney, Buch, Shilpa
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7710131/
https://ncbi.nlm.nih.gov/pubmed/33304479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jev2.12027
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