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Loss of β‐Actin Leads to Accelerated Mineralization and Dysregulation of Osteoblast‐Differentiation Genes during Osteogenic Reprogramming

Actin plays fundamental roles in both the cytoplasm and the cell nucleus. In the nucleus, β‐actin regulates neuronal reprogramming by consolidating a heterochromatin landscape required for transcription of neuronal gene programs, yet it remains unknown whether it has a role in other differentiation...

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Vydáno v:Adv Sci (Weinh)
Hlavní autoři: Gjorgjieva, Tamara, Xie, Xin, Commins, Patrick, Pasricha, Renu, Mahmood, Syed Raza, Gunsalus, Kristin C., Naumov, Panče, Percipalle, Piergiorgio
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7709978/
https://ncbi.nlm.nih.gov/pubmed/33304760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/advs.202002261
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