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Ice recrystallisation inhibiting polymers prevent irreversible protein aggregation during solvent-free cryopreservation as additives and as covalent polymer-protein conjugates

Protein storage and transport is essential to deliver therapies (biologics), enzymes for biotechnological applications, and underpins fundamental structural and molecular biology. To enable proteins to be stored and transported it is often essential to freeze them, requiring cryoprotectants such as...

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Bibliografske podrobnosti
izdano v:Eur Polym J
Main Authors: Fayter, Alice E.R., Hasan, Muhammad, Congdon, Thomas R., Kontopoulou, Ioanna, Gibson, Matthew I.
Format: Artigo
Jezik:Inglês
Izdano: Pergamon Press 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7709485/
https://ncbi.nlm.nih.gov/pubmed/33311718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.eurpolymj.2020.110036
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