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Mitochondrion as a Selective Target for the Treatment of Atherosclerosis: Role of Mitochondrial DNA Mutations and Defective Mitophagy in the Pathogenesis of Atherosclerosis and Chronic Inflammation

BACKGROUND: Atherosclerosis is a chronic inflammatory condition that affects different arteries in the human body and often leads to severe neurological complications, such as stroke and its sequelae. Affected blood vessels develop atherosclerotic lesions in the form of focal thickening of the intim...

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Detalhes bibliográficos
Publicado no:Curr Neuropharmacol
Main Authors: Orekhov, Alexander N., Poznyak, Anastasia V., Sobenin, Igor A., Nikifirov, Nikita N., Ivanova, Ekaterina A.
Formato: Artigo
Idioma:Inglês
Publicado em: Bentham Science Publishers 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7709151/
https://ncbi.nlm.nih.gov/pubmed/31744449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1570159X17666191118125018
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