High rate of major drug–drug interactions of lopinavir–ritonavir for COVID-19 treatment

The impact of drug–drug interactions (DDI) between ritonavir-boosted lopinavir (LPV-r) to treat patients with coronavirus disease 2019 (COVID-19) and commonly used drugs in clinical practice is not well-known. Thus, we evaluated the rate and severity of DDI between LPV-r for COVID-19 treatment and c...

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Udgivet i:Sci Rep
Main Authors: Macías, Juan, Pinilla, Ana, Lao-Dominguez, Francisco A., Corma, Anaïs, Contreras-Macias, Enrique, González-Serna, Alejandro, Gutierrez-Pizarraya, Antonio, Fernández-Fuertes, Marta, Morillo-Verdugo, Ramón, Trigo, Marta, Real, Luis M., Pineda, Juan A.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7708981/
https://ncbi.nlm.nih.gov/pubmed/33262433
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-78029-3
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