Pluripotent epigenetic regulator OBP-801 maintains filtering blebs in glaucoma filtration surgery model

Inhibition of fibrosis is indispensable for maintaining filtering blebs after glaucoma filtration surgery (GFS). The purpose of this study was to investigate the ability of a pluripotent epigenetic regulator OBP-801 (OBP) to ameliorate extracellular matrix formation in a rabbit model of GFS. Rabbits...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Yamamoto, Yuji, Mukai, Atsushi, Ikushima, Toru, Urata, Yasuo, Kinoshita, Shigeru, Hamuro, Junji, Ueno, Morio, Sotozono, Chie
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7708845/
https://ncbi.nlm.nih.gov/pubmed/33262357
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-77811-7
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