Inhibition of EZH2 ameliorates bacteria-induced liver injury by repressing RUNX1 in dendritic cells

Fulminant hepatic failure (FHF) is a clinical syndrome characterized by a sudden and severe impairment in liver function. However, the precise mechanism of immune dysregulation that is significant to FHF pathogenesis remains unclear. Enhancer of zeste homolog 2 (EZH2) has been implicated in inflamma...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Wang, Yanan, Wang, Qiwei, Wang, Bei, Gu, Yuting, Yu, Hongshuang, Yang, Wanlin, Ren, Xiaohui, Qian, Fengtao, Zhao, Xiaonan, Xiao, Yichuan, Zhang, Yanyun, Jin, Min, Zhu, Meiling
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7708645/
https://ncbi.nlm.nih.gov/pubmed/33262329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-03219-w
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