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Organoleptic assessment and median lethal dose determination of oral aldicarb in rats

Aldicarb, a carbamate pesticide, is an acetylcholinesterase (AChE) inhibitor, with oral median lethal dose (LD(50)) estimates in rats ranging from 0.46 to 0.93 mg/kg. A three-phase approach was used to comprehensively assess aldicarb as an oral-ingestion hazard. First, the solubility of aldicarb in...

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Udgivet i:Ann N Y Acad Sci
Main Authors: Rice, Nathaniel C., Rauscher, Noah A., Moffett, Mark C., Myers, Todd M.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7708594/
https://ncbi.nlm.nih.gov/pubmed/32761625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nyas.14448
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