Auditory function analysis in immunodeficient STAT1 knock-out mice: considerations for viral infection models

The STAT1 knock-out (KO) mouse is a frequently used transgenic immunodeficient strain to model human viral and bacterial diseases. The Lassa fever model was established in the STAT1 KO mice mimicking phenotypes seen in human patients including deafness in survivors. This model develops hearing loss...

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Bibliografiske detaljer
Udgivet i:Neurosci Lett
Main Authors: Suzuki, Tomoharu, Maruyama, Junki, Cook, Rebecca, Urata, Shinji, Paessler, Slobodan, Makishima, Tomoko
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7708419/
https://ncbi.nlm.nih.gov/pubmed/33069812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2020.135427
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