An Immunomodulatory Gallotanin-Rich Fraction From Caesalpinia spinosa Enhances the Therapeutic Effect of Anti-PD-L1 in Melanoma

PD-1/PD-L1 pathway plays a role in inhibiting immune response. Therapeutic antibodies aimed at blocking the PD-1/PD-L1 interaction have entered clinical development and have been approved for a variety of cancers. However, the clinical benefits are reduced to a group of patients. The research in com...

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Publicado en:Front Immunol
Autores principales: Lasso, Paola, Gomez-Cadena, Alejandra, Urueña, Claudia, Donda, Alena, Martinez-Usatorre, Amaia, Romero, Pedro, Barreto, Alfonso, Fiorentino, Susana
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7708328/
https://ncbi.nlm.nih.gov/pubmed/33312174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.584959
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