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KLHL17/Actinfilin, a brain-specific gene associated with infantile spasms and autism, regulates dendritic spine enlargement

BACKGROUND: Dendritic spines, the actin-rich protrusions emerging from dendrites, are the subcellular locations of excitatory synapses in the mammalian brain. Many actin-regulating molecules modulate dendritic spine morphology. Since dendritic spines are neuron-specific structures, it is reasonable...

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Detalhes bibliográficos
Publicado no:J Biomed Sci
Main Authors: Hu, Hsiao-Tang, Huang, Tzyy-Nan, Hsueh, Yi-Ping
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7708131/
https://ncbi.nlm.nih.gov/pubmed/33256713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-020-00696-1
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