Regulation of RUVBL1-RUVBL2 AAA-ATPases by the nonsense-mediated mRNA decay factor DHX34, as evidenced by Cryo-EM

Nonsense-mediated mRNA decay (NMD) is a surveillance pathway that degrades aberrant mRNAs and also regulates the expression of a wide range of physiological transcripts. RUVBL1 and RUVBL2 AAA-ATPases form an hetero-hexameric ring that is part of several macromolecular complexes such as INO80, SWR1,...

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Publicado en:eLife
Autores principales: López-Perrote, Andres, Hug, Nele, González-Corpas, Ana, Rodríguez, Carlos F, Serna, Marina, García-Martín, Carmen, Boskovic, Jasminka, Fernandez-Leiro, Rafael, Caceres, Javier F, Llorca, Oscar
Formato: Artigo
Lenguaje:Inglês
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Structural Biology and Molecular Biophysics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7707835/
https://ncbi.nlm.nih.gov/pubmed/33205750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.63042
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