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Nucleophilic Dearomatization of N-Heteroaromatics Enabled by Lewis Acids and Copper Catalysis

[Image: see text] Dearomative functionalization of heteroaromatics, a readily available chemical feedstock, is one of the most straightforward approaches for the synthesis of three-dimensional, chiral heterocyclic systems, important synthetic building blocks for both synthetic chemistry and drug dis...

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Publicat a:J Am Chem Soc
Autors principals: Yan, Xingchen, Ge, Luo, Castiñeira Reis, Marta, Harutyunyan, Syuzanna R.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2020
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7707624/
https://ncbi.nlm.nih.gov/pubmed/33171043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.0c09974
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