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Perturbation of the human gastrointestinal tract microbial ecosystem by oral drugs to treat chronic disease results in a spectrum of individual specific patterns of extinction and persistence of dominant microbial strains

BACKGROUND: Oral drugs can have side effects such as diarrhea that indicate the perturbation of the gut microbial community. To further understand the dynamics of perturbation, we have assessed the strain relatedness of samples from previously published data sets from pre and post bowel evacuation,...

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Veröffentlicht in:PLoS One
Hauptverfasser: Koo, Hyunmin, Morrow, Casey D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2020
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7707550/
https://ncbi.nlm.nih.gov/pubmed/33259474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0242021
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