Predicting response and toxicity to PD-1 inhibition using serum autoantibodies identified from immuno-mass spectrometry

Background: Validated biomarkers are needed to identify patients at increased risk of immune-related adverse events (irAEs) to immune checkpoint blockade (ICB). Antibodies directed against endogenous antigens can change after exposure to ICB. Methods: Patients with different solid tumors stratified...

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Udgivet i:F1000Res
Main Authors: Music, Milena, Iafolla, Marco, Soosaipillai, Antoninus, Batruch, Ihor, Prassas, Ioannis, Pintilie, Melania, Hansen, Aaron R., Bedard, Philippe L., Lheureux, Stephanie, Spreafico, Anna, Razak, Albiruni Abdul, Siu, Lillian L., Diamandis, Eleftherios P.
Format: Artigo
Sprog:Inglês
Udgivet: F1000 Research Limited 2020
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7707117/
https://ncbi.nlm.nih.gov/pubmed/33299547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12688/f1000research.22715.1
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