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Established and emerging therapeutic uses of PDE type 5 inhibitors in cardiovascular disease
PDE type 5 inhibitors (PDE5Is), such as sildenafil, tadalafil and vardenafil, are a class of drugs used to prolong the physiological effects of NO/cGMP signalling in tissues through the inhibition of cGMP degradation. Although these agents were originally developed for the treatment of hypertension...
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| Publicado no: | Br J Pharmacol |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7707100/ https://ncbi.nlm.nih.gov/pubmed/31721165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14920 |
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