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Nicotine stimulates ion transport via metabotropic β4 subunit containing nicotinic ACh receptors

BACKGROUND AND PURPOSE: Mucociliary clearance is an innate immune process of the airways, essential for removal of respiratory pathogens. It depends on ciliary beat and ion and fluid homeostasis of the epithelium. We have shown that nicotinic ACh receptors (nAChRs) activate ion transport in mouse tr...

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Bibliografiske detaljer
Udgivet i:Br J Pharmacol
Main Authors: Kumar, Praveen, Scholze, Petra, Fronius, Martin, Krasteva‐Christ, Gabriela, Hollenhorst, Monika I.
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7707097/
https://ncbi.nlm.nih.gov/pubmed/32959891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.15270
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