Cytokine activin C ameliorates chronic neuropathic pain in peripheral nerve injury rodents by modulating the TRPV1 channel

BACKGROUND AND PURPOSE: The cytokine activin C is mainly expressed in small‐diameter dorsal root ganglion (DRG) neurons and suppresses inflammatory pain. However, the effects of activin C in neuropathic pain remain elusive. EXPERIMENTAL APPROACH: Male rats and wild‐type and TRPV1 knockout mice with...

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Gepubliceerd in:Br J Pharmacol
Hoofdauteurs: Huang, Ya‐Kun, Lu, Yu‐Gang, Zhao, Xin, Zhang, Jing‐Bing, Zhang, Feng‐Ming, Chen, Yong, Bi, Ling‐Bo, Gu, Jia‐Hui, Jiang, Zuo‐Jie, Wu, Xiao‐Man, Li, Qing‐Yi, Liu, Yanli, Shen, Jian‐Xin, Liu, Xing‐Jun
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2020
Onderwerpen:
Research Papers
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7707095/
https://ncbi.nlm.nih.gov/pubmed/33095918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.15284
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