Glycogen synthase kinase‐3 inhibition rescues sex‐dependent contextual fear memory deficit in human immunodeficiency virus‐1 transgenic mice

BACKGROUND AND PURPOSE: A significant number of HIV‐1 patients on antiretroviral therapy develop HIV‐associated neurocognitive disorders (HAND). Evidence indicate that biological sex may regulate HAND pathogenesis, but the mechanisms remain unknown. We investigated synaptic mechanisms associated wit...

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Udgivet i:Br J Pharmacol
Main Authors: Moidunny, Shamsudheen, Benneyworth, Michael A., Titus, David J., Beurel, Eleonore, Kolli, Udhghatri, Meints, Joyce, Jalodia, Richa, Ramakrishnan, Sundaram, Atkins, Coleen M., Roy, Sabita
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
Fag:
Research Papers
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7707089/
https://ncbi.nlm.nih.gov/pubmed/33080056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.15288
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