Multifaceted WNT Signaling at the Crossroads Between Epithelial-Mesenchymal Transition and Autophagy in Glioblastoma

Tumor cells can employ epithelial-mesenchymal transition (EMT) or autophagy in reaction to microenvironmental stress. Importantly, EMT and autophagy negatively regulate each other, are able to interconvert, and both have been shown to contribute to drug-resistance in glioblastoma (GBM). EMT has been...

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Bibliographische Detailangaben
Veröffentlicht in:Front Oncol
Hauptverfasser: Coelho, Bárbara Paranhos, Fernandes, Camila Felix de Lima, Boccacino, Jacqueline Marcia, Souza, Maria Clara da Silva, Melo-Escobar, Maria Isabel, Alves, Rodrigo Nunes, Prado, Mariana Brandão, Iglesia, Rebeca Piatniczka, Cangiano, Giovanni, Mazzaro, Giulia La Rocca, Lopes, Marilene Hohmuth
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2020
Schlagworte:
Oncology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7706883/
https://ncbi.nlm.nih.gov/pubmed/33312955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.597743
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