Glioblastoma stem cells induce quiescence in surrounding neural stem cells via Notch signaling

There is increasing evidence demonstrating that adult neural stem cells (NSCs) are a cell of origin of glioblastoma. Here we analyzed the interaction between transformed and wild-type NSCs isolated from the adult mouse subventricular zone niche. We found that transformed NSCs are refractory to quies...

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Detalhes bibliográficos
Publicado no:Genes Dev
Main Authors: Lawlor, Katerina, Marques-Torrejon, Maria Angeles, Dharmalingham, Gopuraja, El-Azhar, Yasmine, Schneider, Michael D., Pollard, Steven M., Rodríguez, Tristan A.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2020
Assuntos:
Research Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7706704/
https://ncbi.nlm.nih.gov/pubmed/33184225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.336917.120
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