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Senescence and the SASP: many therapeutic avenues

Cellular senescence is a stress response that elicits a permanent cell cycle arrest and triggers profound phenotypic changes such as the production of a bioactive secretome, referred to as the senescence-associated secretory phenotype (SASP). Acute senescence induction protects against cancer and li...

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Dettagli Bibliografici
Pubblicato in:Genes Dev
Autori principali: Birch, Jodie, Gil, Jesús
Natura: Artigo
Lingua:Inglês
Pubblicazione: Cold Spring Harbor Laboratory Press 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7706700/
https://ncbi.nlm.nih.gov/pubmed/33262144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.343129.120
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