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Senescence and the SASP: many therapeutic avenues
Cellular senescence is a stress response that elicits a permanent cell cycle arrest and triggers profound phenotypic changes such as the production of a bioactive secretome, referred to as the senescence-associated secretory phenotype (SASP). Acute senescence induction protects against cancer and li...
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| Veröffentlicht in: | Genes Dev |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Cold Spring Harbor Laboratory Press
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7706700/ https://ncbi.nlm.nih.gov/pubmed/33262144 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.343129.120 |
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