Pathogenic effects of inhibition of mTORC1/STAT3 axis facilitates Staphylococcus aureus-induced pyroptosis in human macrophages

BACKGROUND: Pyroptosis is a recently identified pathway of caspase-mediated cell death in response to microbes, lipopolysaccharide, or chemotherapy in certain types of cells. However, the mechanism of how pyroptosis is regulated is not well-established. METHODS: Herein, the intracellular bacteria we...

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Detalhes bibliográficos
Publicado no:Cell Commun Signal
Main Authors: Yao, Ruiyuan, Chen, Yuhao, Hao, Huifang, Guo, Zhixin, Cheng, Xiaoou, Ma, Yuze, Ji, Qiang, Yang, Xiaoru, Wang, Yanfeng, Li, Xihe, Wang, Zhigang
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7706204/
https://ncbi.nlm.nih.gov/pubmed/33256738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-020-00677-9
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