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Synthesis of imidazo[1,5-a]pyridines via cyclocondensation of 2-(aminomethyl)pyridines with electrophilically activated nitroalkanes

Imidazo[1,5-a]pyridines were efficiently prepared via the cyclization of 2-picolylamines with nitroalkanes electrophilically activated in the presence of phosphorous acid in polyphosphoric acid (PPA) medium.

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Détails bibliographiques
Publié dans:Beilstein J Org Chem
Auteurs principaux: Aksenov, Dmitrii A, Arutiunov, Nikolai A, Maliuga, Vladimir V, Aksenov, Alexander V, Rubin, Michael
Format: Artigo
Langue:Inglês
Publié: Beilstein-Institut 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7705866/
https://ncbi.nlm.nih.gov/pubmed/33299488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.16.239
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