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Pharmacological targeting of c-FLIP(L) and Bcl-2 family members promotes apoptosis in CD95L-resistant cells
The development of efficient combinatorial treatments is one of the key tasks in modern anti-cancer therapies. An apoptotic signal can either be induced by activation of death receptors (DR) (extrinsic pathway) or via the mitochondria (intrinsic pathway). Cancer cells are characterized by deregulati...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7705755/ https://ncbi.nlm.nih.gov/pubmed/33257694 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-76079-1 |
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