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An in silico approach to analyze HCV genotype-specific binding-site variation and its effect on drug–protein interaction

Genotype variation in viruses can affect the response of antiviral treatment. Several studies have established approaches to determine genotype-specific variations; however, analyses to determine the effect of these variations on drug–protein interactions remain unraveled. We present an in-silico ap...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Khalid, Ramsha, Anwar, Muhammad Faraz, Raees, Muhammad Aanish, Naeem, Sadaf, Abidi, Syed Hani, Ali, Syed
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7705671/
https://ncbi.nlm.nih.gov/pubmed/33257748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-77720-9
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