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Glutathione metabolism is essential for self-renewal and chemoresistance of pancreatic cancer stem cells
BACKGROUND: Cellular metabolism regulates stemness in health and disease. A reduced redox state is essential for self-renewal of normal and cancer stem cells (CSCs). However, while stem cells rely on glycolysis, different CSCs, including pancreatic CSCs, favor mitochondrial metabolism as their domi...
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| Veröffentlicht in: | World J Stem Cells |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Baishideng Publishing Group Inc
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7705467/ https://ncbi.nlm.nih.gov/pubmed/33312407 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4252/wjsc.v12.i11.1410 |
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