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Participation of Endosomes in Toll-Like Receptor 3 Transportation Pathway in Murine Astrocytes

TLR3 provides immediate type I IFN response following entry of stimulatory PAMPs into the CNS, as it is in HSV infection. The receptor plays a vital role in astrocytes, contributing to rapid infection sensing and suppression of viral replication, precluding the spread of virus beyond neurons. The ro...

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Detalhes bibliográficos
Publicado no:Front Cell Neurosci
Main Authors: Mielcarska, Matylda B., Gregorczyk-Zboroch, Karolina P., Szulc-Dąbrowska, Lidia, Bossowska-Nowicka, Magdalena, Wyżewski, Zbigniew, Cymerys, Joanna, Chodkowski, Marcin, Kiełbik, Paula, Godlewski, Michał M., Gieryńska, Małgorzata, Toka, Felix N.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7705377/
https://ncbi.nlm.nih.gov/pubmed/33281554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2020.544612
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