Quality by Design (QbD)-Based Numerical and Graphical Optimization Technique for the Development of Osmotic Pump Controlled-Release Metoclopramide HCl Tablets

PURPOSE: To develop the osmotically controlled-release gastroprokinetic metoclopramide HCl tablets, using quality by design (QbD)-numerical and graphical optimization technique for the treatment of gastroparesis and prophylaxis of delayed nausea and vomiting induced by low-high emetogenic chemothera...

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Bibliographische Detailangaben
Veröffentlicht in:Drug Des Devel Ther
Hauptverfasser: Farooqi, Sadaf, Yousuf, Rabia Ismail, Shoaib, Muhammad Harris, Ahmed, Kamran, Ansar, Sabah, Husain, Tazeen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Dove 2020
Schlagworte:
Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7705261/
https://ncbi.nlm.nih.gov/pubmed/33273807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S278918
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