Topical delivery of a small molecule RUNX1 transcription factor inhibitor for the treatment of proliferative vitreoretinopathy

Proliferative vitreoretinopathy (PVR) is the leading cause of retinal detachment surgery failure. Despite significant advances in vitreoretinal surgery, it still remains without an effective prophylactic or therapeutic medical treatment. After ocular injury or retinal detachment, misplaced retinal c...

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Publicado no:Sci Rep
Main Authors: Delgado-Tirado, Santiago, Amarnani, Dhanesh, Zhao, Guannan, Rossin, Elizabeth J., Eliott, Dean, Miller, John B., Greene, Whitney A., Ramos, Leslie, Arevalo-Alquichire, Said, Leyton-Cifuentes, David, Gonzalez-Buendia, Lucia, Isaacs-Bernal, Daniela, Whitmore, Hannah A. B., Chmielewska, Natalia, Duffy, Brandon V., Kim, Eric, Wang, Heuy-Ching, Ruiz-Moreno, Jose M., Kim, Leo A., Arboleda-Velasquez, Joseph F.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7705016/
https://ncbi.nlm.nih.gov/pubmed/33257736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-77254-0
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