MicroRNA-206 Antagomir Enriched Extracellular Vesicles Attenuate Lung Ischemia-Reperfusion Injury Via CXCL1 Regulation in Alveolar Epithelial Cells

BACKGROUND: Our hypothesis is that the immunomodulatory capacities of mesenchymal stem cell (MSC)-derived extracellular vesicles (EVs) can be enhanced by specific microRNAs to effectively attenuate post-transplant lung ischemia-reperfusion (IR) injury. METHODS: Expression of miR-206 was analyzed in...

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Bibliografiske detaljer
Udgivet i:J Heart Lung Transplant
Main Authors: Cai, Jun, Gehrau, Ricardo, Tu, Zhenxiao, Leroy, Victoria, Su, Gang, Shang, Junyi, Mas, Valeria R., Emtiazjoo, Amir, Pelaez, Andres, Atkinson, Carl, Machuca, Tiago, Upchurch, Gilbert R., Sharma, Ashish K.
Format: Artigo
Sprog:Inglês
Udgivet: 2020
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7704771/
https://ncbi.nlm.nih.gov/pubmed/33067103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.healun.2020.09.012
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