Adenylate Kinase 4 Modulates the Resistance of Breast Cancer Cells to Tamoxifen through an m(6)A-Based Epitranscriptomic Mechanism

N(6)-methyladenosine (m(6)A) is the most abundant internal modification in mRNA and this methylation constitutes an important regulatory mechanism for the stability and translational efficiency of mRNA. In this study, we found that the protein levels of adenylate kinase 4 (AK4) and m(6)A writer METT...

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Detalhes bibliográficos
Publicado no:Mol Ther
Main Authors: Liu, Xiaochuan, Gonzalez, Gwendolyn, Dai, Xiaoxia, Miao, Weili, Yuan, Jun, Huang, Ming, Bade, David, Li, Lin, Sun, Yuxiang, Wang, Yinsheng
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2020
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7704734/
https://ncbi.nlm.nih.gov/pubmed/32956623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2020.09.007
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