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迷迭香酸激活Parkin介导的线粒体自噬并抑制高糖诱导的心肌细胞肥大
OBJECTIVE: To evaluate the effect of rosmarinic acid (RA) on mitophagy and hypertrophy of cardiomyocytes exposed to high glucose (HG). METHODS: Rat cardiomyocytes (H9c2) exposed to HG (25 mmol/L) were treated with 50 μmol/L RA or with both RA treatment and Parkin siRNA transfection, with the cells c...
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| Gepubliceerd in: | Nan Fang Yi Ke Da Xue Xue Bao |
|---|---|
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
南方医科大学学报编辑部
2020
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7704387/ https://ncbi.nlm.nih.gov/pubmed/33243751 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12122/j.issn.1673-4254.2020.11.14 |
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