Skewed Inactivation of X Chromosome: A Cause of Hemophilia Manifestation in Carrier Females

Hemophilia is an X-linked recessive hereditary disorder that classically affects males due to the presence of only one X chromosome in males. Females are usually carriers due to the presence of counterpart X chromosome, but many times manifestations of hemophilia are seen in heterozygous carrier fem...

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Bibliographic Details
Published in:Cureus
Main Authors: Shoukat, Hafiz Muhammad Hassan, Ghous, Ghulam, Tarar, Zahid Ijaz, Shoukat, Muhammad Mohsin, Ajmal, Namra
Format: Artigo
Language:Inglês
Published: Cureus 2020
Subjects:
Genetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7704156/
https://ncbi.nlm.nih.gov/pubmed/33269146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7759/cureus.11216
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