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Modeling a synthetic aptamer-based riboswitch biosensor sensitive to low hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) concentrations

RNA aptamers are relatively short nucleic acid sequences that bind targets with high affinity, and when combined with a riboswitch that initiates translation of a fluorescent reporter protein, can be used as a biosensor for chemical detection in various types of media. These processes span target bi...

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Udgivet i:PLoS One
Main Authors: Mayo, Michael L., Eberly, Jed O., Crocker, Fiona H., Indest, Karl J.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2020
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7703952/
https://ncbi.nlm.nih.gov/pubmed/33253235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0241664
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