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Folate System Gene Variant rs1801394 66A>G may have a Causal Role in Down Syndrome in the Eastern Indian Population
Down syndrome (DS) is associated with trisomy of the 21(st) chromosome in more than 95% cases. The extra chromosome mostly derives due to abnormal chromosomal segregation, i.e. non-disjunction, during meiosis. Earlier reports showed that abnormal folate metabolism can lead to DNA hypomethylation and...
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| Publicado no: | Int J Mol Cell Med |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Babol University of Medical Sciences
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7703665/ https://ncbi.nlm.nih.gov/pubmed/33274184 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22088/IJMCM.BUMS.9.3.215 |
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