Structure of a protective epitope reveals the importance of acetylation of Neisseria meningitidis serogroup A capsular polysaccharide

Meningococcal meningitis remains a substantial cause of mortality and morbidity worldwide. Until recently, countries in the African meningitis belt were susceptible to devastating outbreaks, largely attributed to serogroup A Neisseria meningitidis (MenA). Vaccination with glycoconjugates of MenA cap...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Henriques, Pedro, Dello Iacono, Lucia, Gimeno, Ana, Biolchi, Alessia, Romano, Maria Rosaria, Arda, Ana, Bernardes, Gonҫalo J. L., Jimenez-Barbero, Jesus, Berti, Francesco, Rappuoli, Rino, Adamo, Roberto
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2020
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7703565/
https://ncbi.nlm.nih.gov/pubmed/33158970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2011385117
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