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Targeting the renin−angiotensin signaling pathway in COVID-19: Unanswered questions, opportunities, and challenges

The role of the renin−angiotensin signaling (RAS) pathway in COVID-19 has received much attention. A central mechanism for COVID-19 pathophysiology has been proposed: imbalance of angiotensin converting enzymes (ACE)1 and ACE2 (ACE2 being the severe acute respiratory syndrome coronavirus 2 [SARS-CoV...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Sriram, Krishna, Loomba, Rohit, Insel, Paul A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7703541/
https://ncbi.nlm.nih.gov/pubmed/33203679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2009875117
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