Comparison of reversal of rat pulmonary fibrosis of nintedanib, pirfenidone, and human umbilical mesenchymal stem cells from Wharton’s jelly

BACKGROUND: The present study compared the effects of antifibrotic medications, pirfenidone, and nintedanib, with transplantation of human umbilical mesenchymal stem cells (HUMSCs) in restoring rat pulmonary fibrosis (PF). METHODS: A stable animal model was established via an intratracheal injection...

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Publicat a:Stem Cell Res Ther
Autors principals: Chu, Kuo-An, Yeh, Chang-Ching, Kuo, Fu-Hsien, Lin, Wen-Ren, Hsu, Chien-Wei, Chen, Tien-Hua, Fu, Yu-Show
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7702727/
https://ncbi.nlm.nih.gov/pubmed/33256831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-020-02012-y
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