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Using Trial Sequential Analysis for estimating the sample sizes of further trials: example using smoking cessation intervention

BACKGROUND: Assessing benefits and harms of health interventions is resource-intensive and often requires feasibility and pilot trials followed by adequately powered randomised clinical trials. Data from feasibility and pilot trials are used to inform the design and sample size of the adequately pow...

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Pubblicato in:BMC Med Res Methodol
Autori principali: Claire, Ravinder, Gluud, Christian, Berlin, Ivan, Coleman, Tim, Leonardi-Bee, Jo
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7702700/
https://ncbi.nlm.nih.gov/pubmed/33256626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12874-020-01169-7
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