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Rapid Access to Azabicyclo[3.3.1]nonanes by a Tandem Diverted Tsuji–Trost Process

A three‐step synthesis of the 2‐azabicyclo[3.3.1]nonane ring system from simple pyrroles, employing a combined photochemical/palladium‐catalysed approach is reported. Substrate scope is broad, allowing the incorporation of a wide range of functionality relevant to medicinal chemistry. Mechanistic st...

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Vydáno v:Chemistry
Hlavní autoři: Steeds, Hannah G., Knowles, Jonathan P., Yu, Wai L., Richardson, Jeffery, Cooper, Katie G., Booker‐Milburn, Kevin I.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7702095/
https://ncbi.nlm.nih.gov/pubmed/32812670
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.202003762
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