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Nrl Is Dispensable for Specification of Rod Photoreceptors in Adult Zebrafish Despite Its Deeply Conserved Requirement Earlier in Ontogeny

The transcription factor NRL (neural retina leucine zipper) has been canonized as the master regulator of photoreceptor cell fate in the retina. NRL is necessary and sufficient to specify rod cell fate and to preclude cone cell fate in mice. By engineering zebrafish, we tested if NRL function has co...

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Detalhes bibliográficos
Publicado no:iScience
Main Authors: Oel, A. Phillip, Neil, Gavin J., Dong, Emily M., Balay, Spencer D., Collett, Keon, Allison, W. Ted
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7702016/
https://ncbi.nlm.nih.gov/pubmed/33299975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.isci.2020.101805
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