Involvement of kindlin‐2 in irisin’s protection against ischaemia reperfusion‐induced liver injury in high‐fat diet‐fed mice

Liver steatosis is associated with increased ischaemia reperfusion (I/R) injury. Our previous studies have shown that irisin, an exercise‐induced hormone, mitigates I/R injury via binding to αVβ5 integrin. However, the effect of irisin on I/R injury in steatotic liver remains unknown. Kindlin‐2 dire...

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Vydáno v:J Cell Mol Med
Hlavní autoři: Zhang, Jia, Ren, Yifan, Bi, Jianbin, Wang, Mengzhou, Zhang, Lin, Wang, Tao, Wei, Shasha, Mou, Xingyi, Lv, Yi, Wu, Rongqian
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2020
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7701503/
https://ncbi.nlm.nih.gov/pubmed/32954626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15910
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