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A Novel Homozygous Intronic Variant in TNNT2 Associates With Feline Cardiomyopathy

BACKGROUND: Hypertrophic cardiomyopathy (HCM) is a genetic disease of the heart and the most common cause of sudden cardiac death in the young. HCM is considered a disease of the sarcomere owing to the large number of mutations in genes encoding sarcomeric proteins. The riddle lies in discovering ho...

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Publié dans:Front Physiol
Auteurs principaux: McNamara, James W., Schuckman, Maggie, Becker, Richard C., Sadayappan, Sakthivel
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2020
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7701303/
https://ncbi.nlm.nih.gov/pubmed/33304277
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2020.608473
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